Avaliação da atividade antimicrobiana do biossurfactante produzido por Pseudomonas fluorescens Slim15

Abstract

Bacterial resistance is a worldwide concern due to the prevalence of infections and the use of drugs to treat them that cause prescription errors and as a consequence there are diagnostic failures resulting from this pharmacological ignorance. The irrational and undue use of antimicrobials provides the ideal conditions to trigger resistance of the microorganisms to these compounds. In this sense, research on biosurfactants has been prominent in the pharmaceutical market, mainly related to the antimicrobial function. Thus, the objective of this work was to evaluate the antimicrobial activity of the biosurfactant produced by the strain Pseudomonas fluorescens Slim15 in the ATCC strains of Candida albicans, Escherichia coli, Staphylococcus aureus and Bacillus subtilis. The production of the biosurfactant was made from the inoculum of Pseudomonas fluorescens Slim15 in mineral saline medium described by Thavassi et al. (2011) and the antimicrobial evaluation tests performed from the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). It was possible to prove the biosurfactant production by the bacterium Pseudomonas fluorescens Slim15 and the antimicrobial activity of the biosurfactant in gram-positive, gram-negative and yeast-fungus strains.